DMF (Dimethylformamide) is a transparent liquid that is miscible with water and most organic solvents, making it an excellent aprotic polar solvent. It can be used in the wet spinning of synthetic fibers such as polyacrylonitrile fibers, in the synthesis of polyurethanes; for plastic film production; also as a paint remover for stripping paint; it can also dissolve certain low-solubility pigments, giving them dye-like characteristics.

In the petrochemical industry, it can be used as a gas absorbent for separating and refining gases. In organic reactions, it is an important intermediate in organic synthesis. In the pesticide industry, it can be used to produce chlordimoform; in medicine, it can be used to synthesize sulfadiazine, doxycycline, cortisone, vitamin B6, idoxuridine, pyrvinium pamoate, pyrantel pamoate, N-formylsarcolysin,抗瘤氨酸 (antitumor amino acid), methoxymerphalan, carmustine, lomustine, tegafur, tranexamic acid, betamethasone, megestrol, anethole trithione, chlorpheniramine, and more. It can also be used in product purification and gas analysis.