Chinese Name: Anhydrous Piperazine

English Alias: 1,4-Diazacyclohexane; Diethylenediamine

CAS Number: 110-85-0

Molecular Formula: C₄H₁₀N₂

Molecular Weight: 86.14

Purity: ≥99.5%

MDL Number: MFCD00005953

Beilstein Number: 102555

EC Number: 203-808-3

Physical Properties:

Boiling Point: 146-148 °C

Melting Point: 107-111 °C

Flash Point: 65 °C

Water Solubility: 150 g/L (20°C)

Appearance: White flaky crystals

Content: 99.5%

Uses: Colorless crystals, hygroscopic, with a typical amine odor, easily soluble in water and glycerol. Anhydrous piperazine is used as a pharmaceutical intermediate, mainly for the production of piperazine phosphate, fluphenazine, and rifampicin, as well as for the manufacture of wetting agents, emulsifiers, dispersants, antioxidants, etc. Anhydrous piperazine can also be used in high-performance polymers.

Hazard Code: C

Hazard Level: 34-42/43-52/53

Safety Level: 22-26-36/37/39-45-61

UN Number: UN2579

Anhydrous piperazine is a colorless crystal. It is an important pharmaceutical intermediate and fine chemical raw material used in high-performance polymers, with a wide range of applications. In recent years, extensive and in-depth research has been conducted on its synthesis process both domestically and internationally. Currently, the main raw materials for synthesizing anhydrous piperazine domestically and internationally include ethanolamine, N-hydroxyethyl ethylenediamine, and polyethylenepolyamine. Anhydrous piperazine must be stored in a dry, ventilated, and light-protected area.

Anhydrous piperazine is an important fine chemical raw material with extremely broad applications. Although anhydrous piperazine has been developed, it has not yet reached full production capacity, and the process requires further refinement. Due to its wide range of uses, the market price of anhydrous piperazine is typically about 2.5 times that of piperazine hexahydrate. Currently, China's production of piperazine, especially anhydrous piperazine, is too low to meet market demand. Of the annual import volume of 2,000–2,500 tons, 90% is anhydrous piperazine. In addition to its use in pharmaceutical intermediates, the applications of piperazine in other fields are continuously expanding. Anhydrous piperazine (PIP)

Piperazine is an important pharmaceutical intermediate and fine chemical raw material with a wide range of applications. In recent years, extensive and in-depth research has been conducted on its synthesis process both domestically and internationally. Although anhydrous piperazine has been developed, it has not yet reached full production capacity, and the process requires further refinement. Due to its wide range of uses, the market price of anhydrous piperazine is typically about 2.5 times that of piperazine hexahydrate. Currently, China's production of piperazine, especially anhydrous piperazine, is too low to meet market demand. Of the annual import volume of 2,000–2,500 tons, 90% is anhydrous piperazine. In addition to its use in pharmaceutical intermediates, the applications of piperazine in other fields are continuously expanding.

Anhydrous piperazine is an important pharmaceutical intermediate and fine chemical raw material with a wide range of applications. In recent years, extensive and in-depth research has been conducted on its synthesis process both domestically and internationally. Anhydrous piperazine is a colorless crystal, hygroscopic, with a typical amine odor, and easily soluble in water and glycerol. As a pharmaceutical intermediate, it is mainly used for the production of piperazine phosphate, fluphenazine, and rifampicin, as well as for the manufacture of wetting agents, emulsifiers, dispersants, antioxidants, etc.

Anhydrous piperazine is primarily used as a raw material for pharmaceutical products. Properties: Anhydrous piperazine appears as white rhombic flaky crystals, is hygroscopic in air, slightly soluble in petroleum ether, benzene, and chloroform, and its aqueous solution is alkaline. Storage: It should be stored in a dry, ventilated warehouse, avoiding direct sunlight. Due to its wide range of uses, the market price of anhydrous piperazine is typically about 2.5 times that of piperazine hexahydrate. Currently, China's production of piperazine, especially anhydrous piperazine, is too low to meet market demand. Of the annual import volume of 2,000–2,500 tons, 90% is anhydrous piperazine. In addition to its use in pharmaceutical intermediates, the applications of piperazine in other fields are continuously expanding.

Due to its wide range of uses, the market price of anhydrous piperazine is typically about 2.5 times that of piperazine hexahydrate. Currently, China's production of piperazine, especially anhydrous piperazine, is too low to meet market demand. Of the annual import volume of 2,000–2,500 tons, 90% is anhydrous piperazine. In addition to its use in pharmaceutical intermediates, the applications of piperazine in other fields are continuously expanding. Anhydrous piperazine is primarily used as a raw material for pharmaceutical products. Properties: Anhydrous piperazine appears as white rhombic flaky crystals, is hygroscopic in air, slightly soluble in petroleum ether, benzene, and chloroform, and its aqueous solution is alkaline. Storage: It should be stored in a dry, ventilated warehouse, avoiding direct sunlight.