Silica gel 100-200 mesh is an adsorption and separation material widely used in chemical, pharmaceutical, petroleum, and other fields. Its core characteristics and applications are as follows:

I. Basic Characteristics

1. Physical Properties

   • Appearance: White powder or granular form with good fluidity, particle size range of 100-200 mesh (corresponding to approximately 75-150 micrometers).
   • Composition: Main component is silicon dioxide (SiO?·nH?O), with stable chemical properties.
   • Thermal Stability: Withstands temperatures up to 500–600°C, with a heating loss (at 150°C) of less than 5%.

2. Structural Parameters

   • Pore Type: Mostly macroporous silica gel, with pore sizes around 80–100 ? (8–10 nm) and pore volume of 0.8–1 ml/g.
   • Specific Surface Area: 300–500 m2/g, providing high adsorption capacity.

II. Core Functions and Separation Principles

• Adsorption Mechanism: Based on the difference in interaction forces between the polarity of substances and the hydroxyl groups on the silica gel surface. Polar substances adsorb strongly and have longer retention times, while non-polar substances elute quickly.
• Separation Advantages: High separation efficiency and clear chromatographic bands, suitable for fine purification of trace components.

III. Main Application Areas

1. Chemical and Petroleum Industries
   • Dearomatization of petroleum products, selective separation of organic gases/liquids.
   • Catalyst support and chromatographic carrier.
2. Pharmaceutical and Biological Fields
   • Purification of active ingredients in traditional Chinese medicine, preparation of high-purity drugs.
   • Separation of biological macromolecules such as proteins and nucleic acids.
3. Laboratory Analysis: Used as a stationary phase in column chromatography for qualitative and quantitative analysis of organic compounds or intermediates.

IV. Key Points for Product Selection

• Type Selection:
  • Industrial Grade: Focuses on cost-effectiveness and large-scale separation, typically packaged in 20 kg/bags.
  • Reagent Grade: Higher purity, suitable for scientific research experiments, commonly packaged in 500 g/bottles.
• Key Indicators: Pay attention to particle size uniformity (affects flow rate), moisture content (preferably ≤5%), and pore size matching the target molecule size.

V. Storage and Usage Precautions

• Storage: Store sealed in a dry environment to avoid moisture absorption, which may reduce performance. Shelf life is typically 12 months.
• Regeneration: Can be reactivated by high-temperature drying (150°C) for multiple cycles of reuse.

With its controllable physical structure and high adsorption efficiency, silica gel 100-200 mesh serves as a fundamental material in separation science. Users can optimize selection based on the polarity, molecular weight, and purity requirements of the target substances, in combination with manufacturer technical support.