4-Fluorophenylmagnesium bromide

4-Fluorophenylmagnesium bromide

CAS No.: 352-13-6

Molecular Formula: C6H4BrFMg

Molecular Weight: 199.30

Basic Information

Appearance: Gray to taupe liquid

Density: 0.980g/ml (20°C)

Boiling Point: 66°C (refers to the solvent, not the solute)

Flash Point: -20°C

Concentration: 1.0M (tetrahydrofuran solution)

Properties

Reacts violently with water: Extremely sensitive to air and moisture, will react violently with water and release flammable fluorobenzene.

Flammable: In humid air, due to the intense exothermic reaction, flammable fluorobenzene will be released.

Stability: Operations and storage should be carried out under the protection of anhydrous and oxygen-free inert gases such as nitrogen or argon. Avoid contact with oxidizers, acids, alcohols, etc. at room temperature.

Applications

Pharmaceutical synthesis: Mainly used in the fields of medicine and fine chemical industry, for example, for the synthesis of antidepressant paroxetine and antiemetic aprepitant, etc.

Packaging/Storage

1. 500ml glass bottles; 200L iron drums and steel cylinders.

2. During the opening process, this product should be isolated from air and moisture as much as possible, and it is best to use it up once opened. If color difference or micro-precipitation is found in the product, it will not affect the product performance.

3. Store at room temperature.